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Bmal1 and beta-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced beta-cell failure in mice

The choice between oral and injectable is not about preference

2024 Oct;32(5):3119-3161

5 The absolute risk increase is small (around 3 extra cases for every 1,000 people taking the medication for a year), and the effect is partly explained by weight loss rather than the medication itself

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